These can co-circulate within a region, and indeed many countries are hyper-endemic for all four serotypes. Subsequent infections (secondary infection) by other serotypes increase the risk of developing severe dengue.ĭengue has distinct epidemiological patterns, associated with the four serotypes of the virus.
However, cross-immunity to the other serotypes after recovery is only partial, and temporary. Recovery from infection is believed to provide lifelong immunity against Today, severe dengue affects most Asian and Latin American countries and has become a leading cause of hospitalization and death among children and adults in these regions.ĭengue is caused by a virus of the Flaviviridae family and there are four distinct, but closely related, serotypes of the virus that cause dengue (DENV-1, DENV-2, DENV-3 and DENV-4). Severe dengue was first recognized in the 1950s during dengue epidemics in the PhilippinesĪnd Thailand. Severe dengue has a higher risk of death when not managed appropriately. Of complications associated with severe bleeding, organ impairment and/or plasma leakage. Although less common, some people develop severe dengue, which can be any number This can range from subclinical disease (people may not know they are even infected) to severe flu-like symptoms in those infected. Dengue is widespread throughout the tropics, with local variations in risk influenced by rainfall, temperature, relative humidity and unplanned rapid urbanization.ĭengue causes a wide spectrum of disease. Mosquitoes are also vectors of chikungunya, yellow fever and Zika viruses. Dengue virus is transmitted by female mosquitoes mainly of the species Aedes aegypti and, to a lesser extent, Ae. Sustained community involvement can improve vector control efforts substantially.ĭengue is a mosquito-borne viral disease that has rapidly spread in all regions of WHO in recent years.
Dengue prevention and control depends on effective vector control measures.There are an estimated 100-400 million infections each year. About half of the world's population is now at risk. The global incidence of dengue has grown dramatically in recent decades.Early detection of disease progression associated with severe dengue, and access to proper medical care lowers fatality rates of severe dengue to below 1%. There is no specific treatment for dengue/severe dengue.Occasionally this develops into a potentially lethal complication, called severe dengue. While many DENV infections produce only mild illness, DENV can cause an acute flu-like illness.It requires management by medical professionals. Severe dengue is a leading cause of serious illness and death in some Asian and Latin American countries.There are four DENV serotypes, meaning that it is possible to be infected four times. The virus responsible for causing dengue, is called dengue virus (DENV).Dengue is a mosquito-borne viral infection, found in tropical and sub-tropical climates worldwide, mostly in urban and semi-urban areas.
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